Description

3,5-Dimethoxybenzyl Chloride is a versatile and reactive organic intermediate characterized by its benzyl chloride core substituted with methoxy groups at the 3 and 5 positions. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential candidates for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive benzyl chloride moiety for structural diversification.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Development: Employed in the research and production of advanced polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Chemistry: Acts as an intermediate in the synthesis of complex dyes and organic pigments.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3,5-Dimethoxybenzyl Chloride
CAS No.	6652-32-0
Molecular Formula	C9H11ClO2
Molecular Weight	186.64 g/mol
Synonyms	1-(Chloromethyl)-3,5-dimethoxybenzene; (3,5-Dimethoxyphenyl)methyl Chloride; 3,5-Dimethoxybenzylchloride; 3,5-Dimethoxy-α-chlorotoluene; α-Chloro-3,5-dimethoxytoluene; Benzene, 1-(chloromethyl)-3,5-dimethoxy-; 3,5-Dimethoxybenzyl Chloride (technical grade)
EINECS	229-672-9

Quality Control

Our 3,5-Dimethoxybenzyl Chloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.