Description

4-Hydroxy-Tetramisole is a key chiral intermediate and metabolite of the anthelmintic agent levamisole. This compound matters for its critical role in the synthesis and analytical profiling of pharmaceutical actives, ensuring precise control over stereochemistry and metabolic pathways. It is primarily needed by pharmaceutical R&D laboratories, manufacturers of active pharmaceutical ingredients (APIs), and analytical service providers focused on veterinary and human medicine.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of levamisole and related chiral pharmaceutical compounds.
• Metabolite Reference Standard: Used as an analytical standard in pharmacokinetic and metabolic studies for drug development and regulatory submissions.
• Veterinary Drug Research: Employed in the research and development of new anthelmintic and immunomodulatory agents for animal health.
• Chiral Resolution Studies: Serves as a model compound in the development and validation of chiral separation methods using HPLC or SFC.
• Biochemical Research: Utilized in studies investigating enzyme inhibition and cellular signaling pathways.
• Quality Control & Impurity Profiling: Acts as a known impurity or reference marker in the quality control testing of levamisole API batches.

Basic Information

Product Name	4-Hydroxy-Tetramisole
CAS No.	6649-26-9
Molecular Formula	C₁₁H₁₂N₂O
Molecular Weight	188.23 g/mol
Synonyms	(S)-(-)-4-Hydroxytetramisole; (S)-4-Hydroxytetramisole; (-)-4-Hydroxytetramisole; Tetramisole-4-ol; (S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazol-4-ol; Levamisole metabolite; NSC 293099
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-Tetramisole is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S-enantiomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.