Description

Cyclobutyl-Acetic Acid CAS NO 6540-33-6 is a versatile carboxylic acid derivative featuring a cyclobutyl ring, serving as a key chiral building block in advanced organic synthesis. Its unique strained-ring structure makes it a valuable intermediate for constructing complex molecular architectures with specific steric and electronic properties. This compound is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its bioisosteric potential.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or modifying agent in the development of specialized polymers with tailored thermal and mechanical properties.
• Flavor and Fragrance Chemistry: Serves as a starting material for synthesizing unique aroma compounds and musk analogs.
• Academic and R&D Laboratories: A fundamental reagent for methodological studies in organic chemistry, including ring-expansion and cross-coupling reactions.

Basic Information

Product Name	Cyclobutyl-Acetic Acid
CAS No.	6540-33-6
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	Cyclobutaneacetic Acid; 2-Cyclobutylacetic Acid; Cyclobutylacetic Acid; (Cyclobutyl)acetic Acid; Cyclobutanecarboxylic Acid, Methyl-; 6540-33-6; NSC 163022
EINECS	229-476-6

Quality Control

Our Cyclobutyl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC for residual solvents, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, and impurity profiles. We support compliance with global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect purity and stability. Keep away from incompatible materials such as strong oxidizing agents, bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.