Description

6-Chloropyridazine-3-carbonyl chloride is a versatile and highly reactive heterocyclic building block, essential for advanced organic synthesis. Its value lies in its dual functionality, serving as a key precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of pyridazine-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridazine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive components.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring the introduction of a chloropyridazine carboxylic acid derivative.
• Bioconjugation and Probe Synthesis: The reactive acid chloride group enables coupling with amines or alcohols to create fluorescent probes or bioconjugates for biochemical research.

Basic Information

Product Name	6-Chloropyridazine-3-carbonyl chloride
CAS No.	6531-04-0
Molecular Formula	C5H2Cl2N2O
Molecular Weight	176.99 g/mol
Synonyms	3-Chlorocarbonyl-6-chloropyridazine; 6-Chloro-3-pyridazinecarbonyl chloride; 6-Chloropyridazine-3-carboxylic acid chloride; 3,6-Dichloropyridazine-4-carbonyl chloride (alternative numbering); 6-Chloro-pyridazine-3-carbonyl chloride; 6-Chloro-3-pyridazinylcarbonyl chloride; 6531-04-0; 6-Chloropyridazine-3-COCl
EINECS	Contact for details

Quality Control

Every batch of 6-Chloropyridazine-3-carbonyl chloride is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO-aligned manufacturing for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.