Description

Chloridosulfurous Acid Ethyl Ester is a specialized organosulfur reagent primarily used as a chlorosulfonating agent in organic synthesis. This compound is valued for its ability to introduce the chlorosulfonyl (-SO2Cl) functional group, a key intermediate in the production of sulfonamides and other sulfur-containing fine chemicals. It serves as a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of sulfonamide-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that contain sulfonylurea or sulfonamide moieties.
• Polymer & Material Science: Acts as a modifying agent or cross-linker precursor for specialty polymers and functional surfaces.
• Organic Synthesis Reagent: Employed in research laboratories for the chlorosulfonation of aromatic and aliphatic compounds.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of sulfonated dyes and colorants.

Basic Information

Product Name	Chloridosulfurous Acid Ethyl Ester
CAS No.	6378-11-6
Molecular Formula	C2H5ClO2S
Molecular Weight	128.58 g/mol
Synonyms	Ethyl Chlorosulfite; Ethyl Chlorosulfonate; Chlorosulfurous Acid Ethyl Ester; Ethoxysulfonyl Chloride; NSC 9375; Ethyl ester of chlorosulfurous acid; Sulfurochloridic acid, ethyl ester
EINECS	228-941-4

Quality Control

Our Chloridosulfurous Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by titration and purity verification by gas chromatography (GC), to ensure it meets precise specifications for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.