Description

2-Bromo-4-tert-Butylbenzoic Acid is a versatile halogenated aromatic carboxylic acid derivative, valued for its role as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a bromine substituent and a bulky tert-butyl group, makes it particularly useful for constructing complex molecules and facilitating specific coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the bromine atom serves as a handle for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis, such as palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where the introduction of a bulky, lipophilic group modifies material properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and constructing molecular libraries for screening.

Basic Information

Product Name	2-Bromo-4-tert-Butylbenzoic Acid
CAS No.	6332-96-3
Molecular Formula	C11H13BrO2
Molecular Weight	257.13 g/mol
Synonyms	4-(tert-Butyl)-2-bromobenzoic Acid; 2-Bromo-4-(1,1-dimethylethyl)benzoic Acid; 2-Bromo-p-tert-butylbenzoic Acid; Benzoic acid, 2-bromo-4-(1,1-dimethylethyl)-; 2-Bromo-4-tert-butyl-benzoic acid; 4-tert-Butyl-2-bromobenzoic Acid
EINECS	228-705-5

Quality Control

Our 2-Bromo-4-tert-Butylbenzoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.