Description

4-Chloro-α-Methylbenzylamine is a versatile chiral amine building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with high stereochemical purity. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its structural motif contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring a specific amine functionality.
• Research & Development: A valuable compound in academic and industrial R&D labs for method development and exploring new synthetic pathways.

Basic Information

Product Name	4-Chloro-α-Methylbenzylamine
CAS No.	6299-02-1
Molecular Formula	C8H10ClN
Molecular Weight	155.62 g/mol
Synonyms	1-(4-Chlorophenyl)ethylamine; (R/S)-1-(4-Chlorophenyl)ethanamine; α-Methyl-4-chlorobenzylamine; p-Chloro-α-methylbenzylamine; 4-Chloro-α-methylbenzylamine; 1-(4-Chlorophenyl)ethan-1-amine; (±)-1-(4-Chlorophenyl)ethylamine
EINECS	228-567-9

Quality Control

Our 4-Chloro-α-Methylbenzylamine is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to determine enantiomeric excess, ensuring it meets the exacting standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is a strong alkali/organic solvent and should be handled with appropriate precautions, separated from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.