Description

4-Chloro-3-Methyl-Benzenesulfonyl Chloride is a versatile and reactive organosulfur compound primarily used as a key synthetic intermediate. Its value lies in its dual functionality, serving as a crucial building block for the introduction of sulfonamide and sulfonate groups into target molecules. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various sulfonamide-based drugs, including diuretics, antibacterial agents, and protease inhibitors.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the sulfonyl chloride moiety is incorporated for bioactivity.
• Dyestuff and Pigment Manufacturing: Serves as an intermediate for creating sulfonated dyes and pigments, enhancing solubility and color properties.
• Polymer Modification: Employed to introduce sulfonyl groups into polymer chains, modifying properties like hydrophilicity, adhesion, and thermal stability.
• Chemical Research & Development: A valuable reagent in organic synthesis for constructing complex molecules in medicinal chemistry and material science projects.
• Liquid Crystal and Electronic Material Precursor: Used in the synthesis of advanced materials for display technologies and electronic applications.

Basic Information

Product Name	4-Chloro-3-Methyl-Benzenesulfonyl Chloride
CAS No.	6291-02-7
Molecular Formula	C7H6Cl2O2S
Molecular Weight	225.09 g/mol
Synonyms	4-Chloro-3-methylbenzenesulfonyl chloride; 3-Methyl-4-chlorobenzenesulfonyl chloride; 2-Chloro-5-methylbenzenesulfonyl chloride; 4-Chloro-m-toluenesulfonyl chloride; 4-Chloro-3-methylphenylsulfonyl chloride; 1-Chloro-4-methyl-2-sulfonylchloridobenzene; p-Chloro-m-toluenesulfonyl chloride; 4-Chloro-3-methylbenzene-1-sulfonyl chloride
EINECS	228-540-8

Quality Control

Our 4-Chloro-3-Methyl-Benzenesulfonyl Chloride is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation via IR and NMR, and precise titration methods, to ensure it meets exacting specifications for sensitive synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.