Description

trans-2-Methylcyclopropanecarboxylic Acid is a versatile cyclopropane derivative carboxylic acid, characterized by its strained three-membered ring structure and a chiral center. This compound is a valuable chiral building block and intermediate in organic synthesis, prized for its ability to impart unique conformational and steric properties to target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and polymers with specific mechanical or optical properties derived from the rigid cyclopropane ring.
• Flavor and Fragrance Chemistry: Acts as an intermediate for creating complex aroma molecules with unique olfactory profiles.
• Academic and R&D Laboratories: A fundamental reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	trans-2-Methylcyclopropanecarboxylic Acid
CAS No.	6202-94-4
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	(1R,2S)-2-Methylcyclopropanecarboxylic Acid; (1S,2R)-2-Methylcyclopropanecarboxylic Acid; trans-2-Methylcyclopropanecarboxylic Acid; 2-Methylcyclopropanecarboxylic Acid, trans-; 2-Methylcyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-methyl-, trans-; (+/-)-trans-2-Methylcyclopropanecarboxylic Acid; DL-trans-2-Methylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our trans-2-Methylcyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. The compound is a strong acid/organic solvent and should be handled with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% (trans isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.