Description

Diosmin Octaacetate is a fully acetylated derivative of the flavonoid diosmin, offering enhanced lipophilicity and stability for advanced formulation work. This high-purity intermediate is critical for researchers and manufacturers requiring a precisely modified flavonoid backbone for pharmaceutical and nutraceutical development. It serves as a key building block for the synthesis of novel therapeutic agents and standardized botanical extracts targeting vascular health and inflammation.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of advanced flavonoid-based drug candidates for venoactive and anti-inflammatory therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmacopeial (e.g., USP, EP) testing of diosmin and related products.
• Nutraceutical Formulation: Employed in the development of enhanced bioavailability formulations for dietary supplements targeting capillary fragility and chronic venous insufficiency.
• Biochemical Research: A valuable tool for studying the structure-activity relationships (SAR) of flavonoids, their metabolism, and acetylated prodrug strategies.
• Cosmeceutical Actives: Incorporated into advanced skincare formulations for its potential antioxidant and microcirculation-enhancing properties.

Basic Information

Product Name	Diosmin Octaacetate
CAS No.	6195-54-6
Molecular Formula	C34H38O19
Molecular Weight	726.66 g/mol
Synonyms	Diosmin Octaacetate; Diosmetin 7-O-rutinoside Octaacetate; 3',5-Dihydroxy-4'-methoxy-7-[α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyloxy]flavone Octaacetate; Diosmin, octaacetate; Barosmin Octaacetate; Venosmine Octaacetate; Daflon Intermediate; Flavonoid Octaacetate Ester
EINECS	Contact for details

Quality Control

Our Diosmin Octaacetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, IR and NMR for identification, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical and research use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.