Description

Glycine, N-[2-(Benzoylthio)-1-oxopropyl]- is a specialized organic compound featuring a benzoylthio-protected thiol group linked to a modified glycine backbone. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in peptide mimetics, enzyme inhibitor design, and prodrug development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or requiring specific thiol-release mechanisms.
• Peptidomimetic Research: Used to incorporate modified amino acid residues into peptide chains to enhance stability, bioavailability, or biological activity.
• Bioconjugation Chemistry: Serves as a reagent for introducing protected thiol functionalities into larger molecules for subsequent labeling or cross-linking.
• Prodrug Synthesis: Employed in designing prodrugs where the benzoylthio moiety acts as a cleavable protecting group for controlled drug release.
• Chemical Biology Tool: Utilized in research to study thiol-dependent biological processes and to develop activity-based probes.
• Fine Chemical Synthesis: Acts as a specialized intermediate for creating complex organic molecules with specific stereochemical or functional group requirements.

Basic Information

Product Name	Glycine, N-[2-(Benzoylthio)-1-oxopropyl]-
CAS No.	6183-01-3
Molecular Formula	C12H13NO3S
Molecular Weight	251.30 g/mol
Synonyms	N-(2-Benzoylthiopropanoyl)glycine; 2-[(2-Benzoylthio)propanoylamino]acetic acid; Benzoylthio-modified glycine derivative; S-Benzoyl-3-mercapto-2-methylpropionylglycine; Bz-S-CH(CH3)-CO-Gly-OH; (2-Benzoylthio-1-oxopropyl)glycine; α-(Benzoylthio)propionylglycine
EINECS	Contact for details

Quality Control

Our Glycine, N-[2-(Benzoylthio)-1-oxopropyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring reliable and traceable raw materials for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.