Description

N,N',N''-Trimethylguanidine is a versatile organic base and a key building block in advanced chemical synthesis. Its strong basicity and unique guanidine structure make it an essential reagent for the production of pharmaceuticals, agrochemicals, and specialty polymers. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and fine chemical industries seeking high-purity intermediates for complex organic transformations.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing guanidine or amidine functional groups.
• Catalyst and Ligand Precursor: Used in the preparation of organocatalysts and as a ligand precursor in coordination chemistry and metal-catalyzed reactions.
• Polymerization Modifier: Acts as a catalyst or chain transfer agent in the production of specialty polymers and resins, influencing molecular weight and polymer architecture.
• Agrochemical Synthesis: Serves as an intermediate in the manufacture of herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed as a strong, non-nucleophilic base in various organic reactions, including deprotonations and cyclizations.
• Research & Development: A valuable tool for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	N,N',N''-Trimethylguanidine
CAS No.	6145-43-3
Molecular Formula	C4H11N3
Molecular Weight	101.15 g/mol
Synonyms	1,1,3-Trimethylguanidine; TMG; N,N,N'-Trimethylguanidine; Guanidine, N,N,N'-trimethyl-; 1,3-Dimethyl-2-methyliminoguanidine; Trimethylguanidine; N,N',N''-Trimethylguanidine base
EINECS	228-143-6

Quality Control

Our N,N',N''-Trimethylguanidine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the rigorous demands of pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.