Description

1-Tosylpyrazole is a versatile and high-purity organic building block, specifically a tosyl-protected pyrazole derivative, essential for advanced synthetic chemistry. Its primary value lies in serving as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research and development. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing pyrazole or heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the pyrazole moiety is a key pharmacophore.
• Organic Synthesis Reagent: Serves as a protected pyrazole derivative for selective functionalization in multi-step synthetic routes, enabling complex molecule assembly.
• Material Science Research: Employed as a precursor for the development of advanced organic materials, including ligands for catalysis or functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	1-Tosylpyrazole
CAS No.	6126-10-9
Molecular Formula	C10H10N2O2S
Molecular Weight	222.26 g/mol
Synonyms	1-(4-Methylphenyl)sulfonyl-1H-pyrazole; 1H-Pyrazole, 1-[(4-methylphenyl)sulfonyl]-; 1-Tosyl-1H-pyrazole; Pyrazole, 1-tosyl-; N-Tosylpyrazole; p-Toluenesulfonylpyrazole; Tosylpyrazole; 4-Methylbenzenesulfonylpyrazole
EINECS	Contact for details

Quality Control

Our 1-Tosylpyrazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to relevant industry standards and can support development projects requiring GMP-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.