Description

Piperazine Dihydrochloride is a versatile organic salt widely used as a key pharmaceutical intermediate and chemical building block. Its primary value lies in its role as a precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly anthelmintics and other therapeutic agents. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking a reliable, high-purity intermediate for complex synthesis.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of anthelmintic drugs (e.g., diethylcarbamazine citrate) and other APIs.
• Chemical Synthesis: Used as a reactant or catalyst in organic synthesis, particularly in the formation of piperazine derivatives and heterocyclic compounds.
• Research & Development: Serves as a standard reagent in medicinal chemistry and biochemical research for developing new therapeutic molecules.
• Agrochemical Production: Intermediate in the manufacture of certain pesticides and plant growth regulators.
• Polymer Industry: Can be utilized as a curing agent or cross-linking agent in epoxy resin systems and polyurethane production.
• Corrosion Inhibitor: Component in formulations for industrial water treatment and metal surface protection.

Basic Information

Product Name	Piperazine Dihydrochloride
CAS No.	6094-40-2
Molecular Formula	C4H10N2·2HCl
Molecular Weight	159.06 g/mol
Synonyms	Piperazine Hydrochloride (1:2); Piperazinium Dichloride; Diethylenediamine Dihydrochloride; 1,4-Diazacyclohexane Dihydrochloride; Piperazine, Dihydrochloride; Piperazine HCl; Piperazine-1,4-diium dichloride
EINECS	228-056-4

Quality Control

Our Piperazine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. We provide comprehensive quality documentation, including Certificates of Analysis (COA) that detail purity, impurity profiles, and physical characteristics. Our production adheres to cGMP principles where applicable, and we can support compliance with major pharmacopoeial standards (USP/EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
pH (5% solution)	3.0 - 5.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.