Description

Cucurbitacin A is a highly bioactive triterpenoid compound belonging to the cucurbitacin family, a class of molecules known for their potent biological effects. Its primary value lies in its role as a critical reference standard and active pharmaceutical ingredient (API) for research and development in pharmacology and natural product chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries focused on developing novel therapeutics, particularly in areas like anti-cancer and anti-inflammatory drug discovery.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and quantification of cucurbitacin content in herbal extracts and finished pharmaceutical products.
• Biomedical Research: Serves as a key investigational compound in preclinical studies exploring its cytotoxic, anti-proliferative, and apoptosis-inducing properties against various cancer cell lines.
• Natural Product Isolation & Analysis: Employed as a benchmark in the isolation, purification, and structural elucidation of related cucurbitacins from plant sources like Cucurbitaceae family plants.
• Bioactivity Screening: Utilized in high-throughput screening assays to evaluate potential anti-inflammatory, hepatoprotective, and other therapeutic activities.
• Academic & Institutional Research: Fundamental for chemical, pharmacological, and toxicological research in universities and R&D institutions to understand structure-activity relationships.
• Nutraceutical Standardization: Acts as a marker compound for the standardization and quality assurance of herbal supplements claiming cucurbitacin-related benefits.

Basic Information

Product Name	Cucurbitacin A
CAS No.	6040-19-3
Molecular Formula	C₃₂H₄₆O₈
Molecular Weight	558.71 g/mol
Synonyms	1,2-Dihydro-α-elaterin; Cucurbitacin A1; α-Elaterin; (23E)-25-Acetoxy-3β,16α,20(R)-trihydroxy-9β-methyl-19-norlanosta-5,23-diene-11,22-dione; NSC 106977; Elatericin A
EINECS	Contact for details

Quality Control

Our Cucurbitacin A is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with relevant standards for research and development purposes. Our commitment is to deliver high-purity, well-characterized materials to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.