Description

cis-1,2-Dimethyl-Cyclopropanedicarboxylic Acid is a high-purity, specialized cyclopropane derivative used as a critical chiral building block in advanced organic synthesis. Its rigid, strained cyclopropane ring and defined stereochemistry make it a valuable intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry, including studies on ring strain and stereoselective reactions.
• Fine Chemical Production: Used in the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Item	Details
Product Name	cis-1,2-Dimethyl-Cyclopropanedicarboxylic Acid
CAS No.	699-49-0
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(1R,2S)-1,2-Dimethylcyclopropane-1,2-dicarboxylic Acid; (1S,2R)-1,2-Dimethylcyclopropane-1,2-dicarboxylic Acid; cis-1,2-Dimethylcyclopropane-1,2-dicarboxylic Acid; 1,2-Dimethylcyclopropane-cis-1,2-dicarboxylic Acid; NSC 163044; Cyclopropanedicarboxylic acid, 1,2-dimethyl-, cis-
EINECS	Contact for details

Quality Control

Every batch of cis-1,2-Dimethyl-Cyclopropanedicarboxylic Acid is produced and tested under a strict quality management system. We ensure high chemical purity and consistent stereochemical integrity through advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.