Description

trans-1,2-Cyclopropanedicarboxylic Acid is a high-purity, versatile cyclopropane derivative serving as a critical chiral building block in advanced organic synthesis. Its rigid, strained three-membered ring structure is essential for constructing complex molecular frameworks with precise stereochemistry. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a rigid, functionalized cyclopropane core.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the cyclopropane moiety enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials with specific structural properties.
• Academic & R&D: A fundamental reagent in organic chemistry laboratories for method development and the study of ring-strain reactivity.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	trans-1,2-Cyclopropanedicarboxylic Acid
CAS No.	696-75-3
Molecular Formula	C5H6O4
Molecular Weight	130.10 g/mol
Synonyms	(1R,2R)-1,2-Cyclopropanedicarboxylic Acid; (1S,2S)-1,2-Cyclopropanedicarboxylic Acid; trans-Cyclopropane-1,2-dicarboxylic Acid; trans-Hexahydrophthalic Acid; Cyclopropane-1,2-dicarboxylic Acid, trans-; NSC 51143; 1,2-Cyclopropanedicarboxylic acid, (1R,2R)-rel-
EINECS	211-795-6

Quality Control

Our trans-1,2-Cyclopropanedicarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay, enantiomeric excess (if applicable), and impurity profiles. Our quality commitment supports applications requiring high-purity standards for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept sealed to prevent absorption of atmospheric moisture, which may affect quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	175 - 185 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.