Description

2-Bromo-4-Chlorophenol is a halogenated phenol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and chlorine substituents, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and stability.
• Material Science: Acts as a monomer or modifying agent in the development of specialty polymers, resins, and flame retardants.
• Dyestuff and Pigment Manufacturing: Serves as an intermediate for creating halogenated dyes and organic pigments.
• Research & Development: Employed in academic and industrial R&D for exploring new chemical reactions, catalytic processes, and material properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings for carbon-carbon and carbon-heteroatom bond formation.

Basic Information

Item	Detail
Product Name	2-Bromo-4-Chlorophenol
CAS No.	695-96-5
Molecular Formula	C6H4BrClO
Molecular Weight	207.45 g/mol
Synonyms	4-Chloro-2-bromophenol; 2-Bromo-4-chlorophenol; 2-Bromo-4-chloro-1-hydroxybenzene; Phenol, 2-bromo-4-chloro-; o-Bromo-p-chlorophenol; 4-Chloro-2-bromo-1-hydroxybenzene; NSC 406119
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chlorophenol is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for intermediate chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its phenolic nature, ensure proper containment to prevent contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.