Description

(1R,3S)-Cyclopent-4-Ene-1,3-Diol CAS NO 694-47-3 is a high-purity, chiral diol building block characterized by its unique fused cyclopentene ring structure. This compound is a valuable synthon in asymmetric synthesis, enabling the construction of complex molecules with precise stereochemistry. It is primarily sought after by research and development chemists in the pharmaceutical and fine chemical industries for applications in drug discovery, process development, and the synthesis of natural products.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly those requiring specific stereocenters.
• Asymmetric Catalysis Ligand Synthesis: Used in the development of novel chiral ligands and organocatalysts for enantioselective transformations.
• Natural Product Synthesis: Serves as a core building block for the total synthesis of terpenes, prostaglandins, and other biologically active natural compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, advanced materials, and high-value agrochemical intermediates.
• Academic & Industrial Research: A critical reagent for methodological development in organic chemistry and for exploring new reaction pathways.

Basic Information

Product Name	(1R,3S)-Cyclopent-4-Ene-1,3-Diol
CAS No.	694-47-3
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	(1R,3S)-1,3-Cyclopentenediol; (1R,3S)-4-Cyclopentene-1,3-diol; cis-4-Cyclopentene-1,3-diol; (1R,3S)-1,3-Dihydroxycyclopent-4-ene; NSC 163045; (1R-cis)-4-Cyclopentene-1,3-diol; Chiral Cyclopentenediol
EINECS	211-777-6

Quality Control

Our (1R,3S)-Cyclopent-4-Ene-1,3-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (assay), enantiomeric excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.