Description

2-Chloroprop-1-En-1-One is a highly reactive and versatile organic building block, primarily valued for its role as a key intermediate in the synthesis of more complex molecules. Its significance lies in its ability to introduce a reactive chlorovinyl ketone moiety, which is crucial for constructing heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new products and optimize synthetic routes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, contributing to novel modes of action.
• Organic Synthesis Reagent: Serves as a versatile electrophile and Michael acceptor in organic chemistry for constructing complex carbon skeletons.
• Material Science Research: Employed in the development of specialty polymers and functional materials that require specific reactive sites.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of certain complex organic dyes and colorants.
• Cross-coupling Reactions: Utilized in palladium-catalyzed and other metal-mediated coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	2-Chloroprop-1-En-1-One
CAS No.	683-51-2
Molecular Formula	C3H3ClO
Molecular Weight	90.51 g/mol
Synonyms	2-Chloro-1-propen-1-one; 2-Chloroacrylaldehyde; 2-Chloroacrylaldehyde; 2-Chloropropenone; 2-Chloro-1-propenone; 2-Chloroacryloyl Chloride (common misnomer); β-Chloroacrylaldehyde; Vinylchloroformyl
EINECS	211-683-9

Quality Control

Our 2-Chloroprop-1-En-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flames. Containers should be kept tightly sealed when not in use to prevent evaporation and moisture ingress.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.