Description

Trimethylsulfonium is a versatile organosulfur compound widely used as a high-performance methylating agent in organic synthesis. Its significance lies in its ability to efficiently transfer methyl groups under relatively mild conditions, making it a valuable reagent for creating complex molecular architectures. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise methylation is a critical step in product development and manufacturing.

Application

• Pharmaceutical Intermediates: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for methylation reactions in drug discovery and process chemistry.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require methyl group incorporation.
• Advanced Material Precursor: Serves as a building block for sulfonium-based ionic liquids, photoacid generators (PAGs) for photoresists, and specialty polymers.
• Organic Synthesis Reagent: Employed in laboratories and pilot plants for methylation of alcohols, phenols, carboxylic acids, and amines.
• Biochemistry Research: Utilized in biochemical studies as a substrate analog or methyl donor in enzymatic and metabolic pathway investigations.
• Catalysis and Ligand Modification: Acts as a methylating agent for modifying catalysts and ligands to alter their reactivity and selectivity.

Basic Information

Product Name	Trimethylsulfonium
CAS No.	676-84-6
Molecular Formula	C₃H₉S⁺ (commonly as iodide salt: C₃H₉SI)
Molecular Weight	77.17 g/mol (cation)
Synonyms	Trimethylsulfonium ion; Sulfonium, trimethyl-; Trimethylsulfonium iodide; TMSI; (CH₃)₃S⁺; Trimethylsulphonium; Trimethylsulfanium; Me₃S⁺
EINECS	211-637-2

Quality Control

Our Trimethylsulfonium products are manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical testing, including assay by titration and identification by FT-IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity, identity, and impurity profiles to meet the stringent requirements of our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (Titration)	≥ 98.0%
Melting Point	220 - 225 °C (dec.)
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.