Description

Pyruvaldehyde Bis(N4-Methylthiosemicarbazone) is a specialized organic compound belonging to the thiosemicarbazone class, known for its ability to form stable metal chelates. This compound matters for its critical role as a precursor or intermediate in the synthesis of radiopharmaceuticals and diagnostic agents, particularly in the development of copper-64 and copper-67 based PET imaging and therapeutic compounds. It is primarily needed by research institutions, pharmaceutical developers, and radiopharmaceutical manufacturers focused on oncology diagnostics and targeted radiotherapy.

Application

• Key precursor for the synthesis of copper-64 (⁶⁴Cu) and copper-67 (⁶⁷Cu) chelators used in Positron Emission Tomography (PET) imaging.
• Intermediate in the development of theranostic agents for targeted cancer diagnosis and therapy.
• Research chemical for studying metal complexation chemistry and redox-active ligands.
• Starting material for producing radiopharmaceutical precursors under Good Manufacturing Practice (GMP) conditions.
• Component in the development of hypoxia-targeting compounds for tumor imaging.
• Reference standard in analytical method development and quality control for related pharmaceutical products.

Basic Information

Product Name	Pyruvaldehyde Bis(N4-Methylthiosemicarbazone)
CAS No.	673-68-7
Molecular Formula	C8H16N6S2
Molecular Weight	260.38 g/mol
Synonyms	Bis(N4-Methyl-3-thiosemicarbazone); Glyoxal Bis(N4-Methylthiosemicarbazone); PTSM; Pyruvaldehyde Bis(N(4)-Methylthiosemicarbazone); 2,3-Butanedione Bis(N4-Methylthiosemicarbazone); ATTSM; Cu-ATSM precursor; Diacetyl Bis(N4-Methylthiosemicarbazone)
EINECS	Contact for details

Quality Control

Our Pyruvaldehyde Bis(N4-Methylthiosemicarbazone) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.