Description

(S)-1,2,3,4,5,6,7,8-Octahydro-2,5,5-Trimethyl-2-Naphthol is a high-purity, chiral intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functionalized decalin structure make it a critical building block for creating complex, optically active molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries seeking to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Employed as a starting material or resolving agent in catalytic asymmetric reactions to induce chirality in target molecules.
• Fragrance and Flavor Chemistry: Used in the research and development of complex, stereospecific aroma chemicals due to its woody, amber-like structural characteristics.
• Material Science Research: Serves as a monomer or functional additive in the development of advanced polymers with specific optical or mechanical properties.
• Agrochemical Synthesis: Acts as an intermediate for creating chiral active ingredients in crop protection products, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, total synthesis projects, and catalysis research.

Basic Information

Product Name	(S)-1,2,3,4,5,6,7,8-Octahydro-2,5,5-Trimethyl-2-Naphthol
CAS No.	670-24-6
Molecular Formula	C₁₃H₂₂O
Molecular Weight	194.31 g/mol
Synonyms	(S)-Octahydro-2,5,5-trimethyl-2-naphthol; (2S)-1,2,3,4,5,6,7,8-Octahydro-2,5,5-trimethyl-2-naphthalenol; (S)-Amberol; (S)-Amberlyn; (S)-Amberketal precursor; (S)-2,5,5-Trimethyl-1,2,3,4,5,6,7,8-octahydro-2-naphthol; (-)-Octahydro-2,5,5-trimethyl-2-naphthol; (S)-Isomer of Octalol
EINECS	211-571-9

Quality Control

Our (S)-1,2,3,4,5,6,7,8-Octahydro-2,5,5-Trimethyl-2-Naphthol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) determination by HPLC, identity confirmation by IR and NMR, and standard pharmacopeial tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications and results is provided with each shipment to ensure full traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.