Description

Hexamidine Diisethionate is a high-purity antimicrobial and preservative agent widely recognized for its efficacy in personal care and pharmaceutical formulations. Its primary value lies in its potent activity against a broad spectrum of bacteria and fungi, making it a critical component for ensuring product safety and shelf-life. This compound is essential for manufacturers in the cosmetics, skincare, and topical pharmaceutical industries seeking a reliable preservative system. Its compatibility with various formulation bases and stability under typical use conditions make it a preferred choice for global suppliers.

Application

• Cosmetic & Personal Care Preservative: Used in creams, lotions, shampoos, and makeup to prevent microbial contamination and spoilage.
• Topical Pharmaceutical Formulations: Incorporated into ointments, gels, and medicated creams as an antimicrobial agent.
• Skincare Products: Found in anti-acne treatments, cleansers, and serums for its antibacterial properties.
• Ophthalmic Solutions: Employed as a preservative in certain eye drop formulations at specified concentrations.
• Wound Care Products: Used in antiseptic creams and sprays to help prevent infection in minor cuts and abrasions.
• Oral Care Products: An active ingredient in some mouthwashes and toothpastes for controlling oral bacteria.

Basic Information

Product Name	Hexamidine Diisethionate
CAS No.	659-40-5
Molecular Formula	C26H44N4O10S2
Molecular Weight	636.78 g/mol
Synonyms	Hexamidine Diisethionate; Hexamidine Di(2-hydroxyethanesulfonate); 4,4'-(Hexane-1,6-diylbis(oxy))dibenzenecarboximidamide Diisethionate; Hexamidine Diisethionate Salt; 1,6-Bis(4-amidinophenoxy)hexane Diisethionate; Hexamidine Dihydroxyethanesulfonate; Hexamidine Isethionate; Hexamidine Bis(2-hydroxyethanesulfonate)
EINECS	Contact for details

Quality Control

Our Hexamidine Diisethionate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is tested against rigorous in-house specifications, which typically include assay, identification, and impurity profile analysis. Certificates of Analysis (COA) documenting purity, residual solvents, and microbiological quality are available for every batch. We adhere to cGMP principles where applicable to support its use in pharmaceutical and high-grade cosmetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets specified requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.