Description

3-Chloro-5-Nitrophenol is a versatile halogenated nitrophenol derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloro and nitro substituents, makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a halogenated phenolic core.
• Agrochemical Synthesis: Used in the manufacture of herbicides, pesticides, and fungicides, where the nitrophenol moiety contributes to biological activity.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing azo dyes and other complex colorants.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and as a starting material for more complex heterocyclic compounds.
• Research & Development: Used in academic and industrial R&D labs for method development and exploring new chemical entities.
• Polymer Chemistry: Can be incorporated as a monomer or modifier to impart specific properties like UV absorption or chemical resistance to polymers.

Basic Information

Product Name	3-Chloro-5-Nitrophenol
CAS No.	618-63-3
Molecular Formula	C6H4ClNO3
Molecular Weight	173.55 g/mol
Synonyms	5-Nitro-3-chlorophenol; 3-Chloro-5-nitro-1-hydroxybenzene; Phenol, 3-chloro-5-nitro-; 1-Hydroxy-3-chloro-5-nitrobenzene; 3-Chloro-5-nitrophenol; 3-Chloro-5-nitrofenol
EINECS	210-559-7

Quality Control

Our 3-Chloro-5-Nitrophenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters including assay (HPLC), identification (IR), and impurity profile. Our quality commitment ensures the material is suitable for demanding GMP-grade synthesis and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	124 - 128 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.