Description

1-Chloro-2-Iodobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chlorine and iodine substituents on the benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily needed by research and development laboratories, pharmaceutical manufacturers, and agrochemical companies for applications in cross-coupling reactions and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates via Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its halogen atoms serve as handles for further functionalization.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating libraries of novel aromatic compounds.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal complexes used in homogeneous catalysis.
• Dye and Pigment Intermediate: Acts as a starting material for the production of certain halogenated dyes and organic pigments.

Basic Information

Item	Detail
Product Name	1-Chloro-2-Iodobenzene
CAS No.	615-41-8
Molecular Formula	C6H4ClI
Molecular Weight	238.45 g/mol
Synonyms	o-Chloroiodobenzene; 2-Chloro-1-Iodobenzene; 2-Chloroidobenzene; 1-Iodo-2-Chlorobenzene; (2-Chlorophenyl)Iodide; Benzene, 1-chloro-2-iodo-; o-Iodochlorobenzene; 615-41-8
EINECS	210-425-6

Quality Control

Our 1-Chloro-2-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.