Description

3-Hydroxy-2-Nitrobenzoic Acid is a versatile nitro-substituted aromatic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and an ortho-nitro group relative to the carboxylic acid, makes it a valuable precursor for synthesizing complex heterocycles, dyes, and pharmaceutical intermediates. This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key starting material or building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted salicylic acid framework.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where its nitro and carboxylic acid functionalities are utilized for further chemical transformations.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants, leveraging the nitro group for chromophore development and the carboxylic acid for solubility modification or polymer attachment.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs as a versatile substrate for reactions such as reduction, cyclization, and functional group interconversion to create novel chemical entities.
• Coordination Chemistry & Ligand Synthesis: The molecule can act as a chelating ligand for metal ions, useful in catalysis or material science applications.
• Chemical Research Standard: Used as an analytical standard or reference compound in quality control and method development within analytical laboratories.

Basic Information

Product Name	3-Hydroxy-2-Nitrobenzoic Acid
CAS No.	602-00-6
Molecular Formula	C7H5NO5
Molecular Weight	183.12 g/mol
Synonyms	2-Nitro-3-hydroxybenzoic Acid; 3-Hydroxy-2-nitrobenzoic Acid; 2-Nitrosalicylic Acid; 3-Hydroxy-2-nitro-benzoic Acid; Benzoic acid, 3-hydroxy-2-nitro-; 3-Carboxy-6-nitrophenol; NSC 403697
EINECS	210-003-5

Quality Control

Our 3-Hydroxy-2-Nitrobenzoic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from techniques such as HPLC, IR spectroscopy, and titration. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Approx. 230 - 235 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.