Description

Methyl Methanesulfonate CAS NO 66-27-3 is a high-purity alkylating agent, a methyl ester of methanesulfonic acid, widely recognized for its role in organic synthesis and research. It serves as a critical reagent for introducing methyl groups into target molecules, enabling the study of DNA alkylation, mutagenesis, and the synthesis of complex intermediates. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable and potent methylating agent for their development and production workflows.

Application

• Pharmaceutical Intermediate Synthesis: Used as a methylating agent in the production of active pharmaceutical ingredients (APIs) and key synthetic intermediates.
• Biochemical Research & Mutagenesis Studies: A standard reagent for inducing DNA alkylation in laboratory studies of genetic damage, repair mechanisms, and mutagenesis.
• Agrochemical Manufacturing: Employed in the synthesis of certain herbicides, pesticides, and plant growth regulators where selective methylation is required.
• Polymer & Material Science: Acts as a monomer or modifying agent in the development of specialty polymers and functional materials.
• Organic Synthesis Reagent: Utilized in various organic transformations, including esterification and etherification reactions, as a source of the methanesulfonate (mesylate) group.
• Laboratory Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in analytical laboratories.

Basic Information

Product Name	Methyl Methanesulfonate
CAS No.	66-27-3
Molecular Formula	C2H6O3S
Molecular Weight	110.13 g/mol
Synonyms	MMS; Methyl Mesylate; Methanesulfonic Acid Methyl Ester; Methyl Methanesulphonate; NSC 50256; Methyl ester of methanesulfonic acid; Mesylic acid methyl ester
EINECS	200-625-0

Quality Control

Our Methyl Methanesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including identity confirmation by FT-IR and quantitative purity determination by GC or HPLC. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.410 - 1.415
Density (20°C)	1.30 - 1.35 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.