Description

4-Phenylbenzylzinc Chloride is an organozinc reagent, specifically a benzylzinc halide, widely used in organic synthesis for the formation of carbon-carbon bonds. This compound is a valuable building block for the introduction of the 4-phenylbenzyl group into complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for cross-coupling reactions and other organometallic transformations.

Application

• As a key reagent in Negishi cross-coupling reactions for the synthesis of biaryl and diarylmethane derivatives.
• For the preparation of pharmaceutical intermediates, particularly in the development of active pharmaceutical ingredients (APIs).
• In the synthesis of liquid crystal materials and organic electronic compounds for advanced material science.
• As a versatile building block in organic chemistry research for constructing complex, functionalized molecules.
• For the alkylation of various electrophiles, including aldehydes, ketones, and acid chlorides.
• In the development of novel ligands and catalysts for asymmetric synthesis.

Basic Information

Product Name	4-Phenylbenzylzinc Chloride
CAS No.	595610-22-3
Molecular Formula	C13H11ClZn
Molecular Weight	267.97 g/mol
Synonyms	(4-Phenylbenzyl)zinc Chloride; Zinc, chlorobis[(4-phenylphenyl)methyl]-; (4-Phenylbenzyl)zinc Chloride Solution; 4-Phenylbenzyl Zinc Chloride; p-Phenylbenzylzinc Chloride; 1,1'-Biphenyl, 4-(chlorozinciomethyl)-; (4-Biphenylylmethyl)zinc Chloride
EINECS	Contact for details

Quality Control

Our 4-Phenylbenzylzinc Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, concentration, and the absence of critical impurities. A Certificate of Analysis (COA) detailing specific results is provided with every shipment, ensuring compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated place. This material is hygroscopic (moisture-sensitive) and easily oxidized. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in Tetrahydrofuran (THF) (Typical)
Assay (Titration)	≥ 95.0%
Identification (IR)	Conforms to structure
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.