Description

2(3H)-Furanone, 3-Acetyldihydro-, (3R)- (9Ci) is a chiral, non-racemic lactone derivative that serves as a valuable synthetic building block and intermediate in advanced organic synthesis. Its defined stereochemistry and functionalized furanone core make it a critical precursor for the development of pharmaceuticals, agrochemicals, and fine chemicals with specific biological activity. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, flavor & fragrance, and specialty chemical industries who require enantiomerically pure materials for complex molecule construction.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anti-inflammatory, or central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is crucial for efficacy.
• Flavor and Fragrance Chemistry: Serves as a precursor for lactone-based flavor compounds (e.g., coconut, peach, dairy notes) and complex fragrance molecules.
• Fine Chemical Manufacturing: Building block for specialty polymers, liquid crystals, and advanced materials requiring precise molecular architecture.
• Asymmetric Catalysis Research: Valuable substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts and methodologies.
• Natural Product Synthesis: Intermediate in the total synthesis of complex natural products containing substituted butyrolactone or dihydrofuranone motifs.

Basic Information

Product Name	2(3H)-Furanone, 3-Acetyldihydro-, (3R)- (9Ci)
CAS No.	594837-91-9
Molecular Formula	C6H8O3
Molecular Weight	128.13 g/mol
Synonyms	(R)-3-Acetyldihydrofuran-2(3H)-one; (3R)-3-Acetyldihydro-2(3H)-furanone; (R)-3-Acetyl-γ-butyrolactone; (R)-3-Acetylbutyrolactone; (R)-α-Acetyl-γ-butyrolactone; (R)-3-Acetyl-4-hydroxybutanoic acid lactone; (3R)-3-Acetyloxolan-2-one; (R)-3-Acetyl-tetrahydro-2-furanone
EINECS	Contact for details

Quality Control

Our (R)-3-Acetyldihydrofuran-2(3H)-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment. We support cGMP and ISO 9001 compliant production for pharmaceutical-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.