Description

Indolizine-6-Carboxylic Acid is a high-value heterocyclic carboxylic acid building block, essential for advanced organic synthesis and pharmaceutical research. Its unique fused-ring structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides with enhanced efficacy.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials and polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biological studies.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry projects.
• Ligand Synthesis: Used to prepare complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Indolizine-6-Carboxylic Acid
CAS No.	588720-42-7
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	1H-Indolizine-6-carboxylic acid; 6-Carboxyindolizine; Indolizine-6-carboxylic acid; 6-Indolizinecarboxylic acid; 1-Azaindole-6-carboxylic acid; Pyrrolo[1,2-a]pyridine-6-carboxylic acid; 6-Carboxy-1-azaindole
EINECS	Contact for details

Quality Control

Our Indolizine-6-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is supplied with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.