Description

2H-Pyran-6-Carboxylicacid,3-Ethyl-3,4-Dihydro-4-Methyl-2-Oxo-,Ethylester,(3R,4S)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters because its unique pyranone scaffold and defined stereochemistry make it a valuable precursor for constructing complex molecules with precise three-dimensional architecture. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in projects targeting complex heterocyclic structures.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce the (3R,4S) configuration into target molecules, crucial for drug efficacy and safety.
• Medicinal Chemistry Research: Serves as a core scaffold for generating compound libraries in hit-to-lead and lead optimization campaigns, exploring new chemical space.
• Agrochemical Development: Employed in the synthesis of advanced intermediates for new crop protection agents and herbicides.
• Academic & Contract Research: Used in university and CRO (Contract Research Organization) settings for methodological studies in organic and heterocyclic chemistry.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of complex, high-value fine chemicals and flavors/fragrances.

Basic Information

Item	Details
Product Name	2H-Pyran-6-Carboxylicacid,3-Ethyl-3,4-Dihydro-4-Methyl-2-Oxo-,Ethylester,(3R,4S)-(9Ci)
CAS No.	588689-97-8
Molecular Formula	C11H16O4
Molecular Weight	212.24 g/mol
Synonyms	(3R,4S)-3-Ethyl-3,4-dihydro-4-methyl-2-oxo-2H-pyran-6-carboxylic acid ethyl ester; Ethyl (3R,4S)-3-ethyl-4-methyl-2-oxo-3,4-dihydro-2H-pyran-6-carboxylate; 2-Oxo-2H-pyran-6-carboxylic acid, 3-ethyl-3,4-dihydro-4-methyl-, ethyl ester, (3R,4S)-; (3R,4S)-3-Ethyl-4-methyl-2-oxo-3,4-dihydro-2H-pyran-6-carboxylic acid ethyl ester; 588689-97-8; (3R,4S)-Dihydro-4-methyl-3-ethyl-2-oxo-2H-pyran-6-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of this chiral intermediate is produced under strict quality control protocols to ensure identity, purity, and stereochemical integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for chiral purity, chemical purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (3R,4S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.