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4-(2-(1-(6-Methylpyridazin-3-Yl)Piperidin-4-Yl)Ethoxy)Benzoic Acid CAS NO 577792-10-0


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CAS No.:577792-10-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-(2-(1-(6-Methylpyridazin-3-Yl)Piperidin-4-Yl)Ethoxy)Benzoic Acid is a high-purity, non-nucleoside reverse transcriptase inhibitor (NNRTI) intermediate of significant pharmaceutical importance. This compound is a critical building block in the research and development of novel antiviral therapeutics, particularly for the treatment of HIV. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in antiviral drug discovery and process chemistry.

Application

  • Pharmaceutical Intermediate: A key synthetic precursor in the production of next-generation non-nucleoside reverse transcriptase inhibitors (NNRTIs) for antiviral applications.
  • Antiviral Drug Discovery: Serves as a core scaffold for medicinal chemistry optimization and structure-activity relationship (SAR) studies targeting HIV and related viruses.
  • Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for active pharmaceutical ingredient (API) manufacturing.
  • Biochemical Research: Employed as a reference standard or probe compound in enzymatic assays and virology research to study reverse transcriptase inhibition mechanisms.
  • Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects where this specific molecular architecture is required for proprietary drug candidates.

Basic Information

Product Name 4-(2-(1-(6-Methylpyridazin-3-Yl)Piperidin-4-Yl)Ethoxy)Benzoic Acid
CAS No. 577792-10-0
Molecular Formula C19H23N3O3
Molecular Weight 341.41 g/mol
Synonyms 4-[2-[1-(6-Methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]benzoic acid; 4-(2-(1-(6-Methylpyridazin-3-yl)piperidin-4-yl)ethoxy)benzoic acid; Benzoic acid, 4-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-; NNRTI Intermediate; 577792-10-0; 4-(2-(1-(6-methyl-3-pyridazinyl)-4-piperidinyl)ethoxy)benzoic acid; 4-(2-(1-(6-methylpyridazin-3-yl)-4-piperidyl)ethoxy)benzoic acid
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Quality Control

Our production of 4-(2-(1-(6-Methylpyridazin-3-Yl)Piperidin-4-Yl)Ethoxy)Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is stable under these conditions but should be handled in accordance with good laboratory practices for strong acid/organic solvent intermediates.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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