Description

4-Chloro-3-Iodoaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the halogenated aniline core provides specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials requiring halogenated aromatic units.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex azo dyes and high-performance pigments.
• Research & Development: A valuable reagent for academic and industrial R&D in organic synthesis and process chemistry.

Basic Information

Product Name	4-Chloro-3-Iodoaniline
CAS No.	573764-31-5
Molecular Formula	C6H5ClIN
Molecular Weight	253.47 g/mol
Synonyms	3-Iodo-4-chloroaniline; 4-Chloro-3-iodobenzenamine; 1-Amino-4-chloro-3-iodobenzene; Benzenamine, 4-chloro-3-iodo-; 4-Chloro-3-iodo-phenylamine; 4-Cl-3-I-C6H3NH2
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Iodoaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity while monitoring for specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.