Description

8-Oxabicyclo[3.2.1]Oct-3-En-2-Ol, 3-Ethyl-, (1R,2R,5S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic ether-alcohol compound, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its rigid, oxygen-containing bicyclic framework provides a versatile scaffold for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development in pharmaceutical synthesis, particularly for creating novel active pharmaceutical ingredients (APIs) and fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis Ligand Precursor: Used in the development of novel chiral ligands and catalysts for enantioselective synthesis.
• Natural Product Synthesis: Serves as a building block for the total synthesis of complex natural products containing oxabicyclic motifs.
• Agrochemical Research: Employed in the development of new, stereospecific pesticides and herbicides.
• Material Science Monomer: Potential monomer for creating specialized polymers with unique thermal and mechanical properties.
• Academic & R&D: A valuable reference standard and starting material in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Item	Details
Product Name	8-Oxabicyclo[3.2.1]Oct-3-En-2-Ol, 3-Ethyl-, (1R,2R,5S)-Rel- (9Ci)
CAS No.	571167-47-0
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	rel-(1R,2R,5S)-3-Ethyl-8-oxabicyclo[3.2.1]oct-3-en-2-ol; 3-Ethyl-8-oxabicyclo[3.2.1]oct-3-en-2-ol, (1R,2R,5S)-rel-; Bicyclo[3.2.1]oct-3-en-2-ol, 8-oxa-3-ethyl-, (1R,2R,5S)-rel-; 8-Oxabicyclo[3.2.1]oct-3-en-2-ol, 3-ethyl-, (1R,2R,5S)-rel-; (rel)-(1R,2R,5S)-3-Ethyl-8-oxabicyclo[3.2.1]oct-3-en-2-ol; Chiral Oxabicyclic Alcohol; 3-Ethyl-8-oxabicyclo[3.2.1]oct-3-en-2-ol (rel-isomer)
EINECS	Contact for details

Quality Control

Our 8-Oxabicyclo[3.2.1]Oct-3-En-2-Ol, 3-Ethyl-, (1R,2R,5S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and enantiomeric excess. We support compliance with ICH guidelines and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.