Description

3-Bromo-5-Chloro-2-Methoxyaniline is a high-purity, multi-functional aromatic amine building block with significant commercial value in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its halogenated aniline core contributes to biological activity.
• Dye and Pigment Manufacturing: Serves as a building block for advanced azo dyes, pigments, and colorants used in textiles, inks, and polymers.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and photoactive materials due to its electron-donating amine and electron-withdrawing halogen groups.
• Cross-Coupling Reactions: An excellent substrate for Buchwald-Hartwig amination, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	3-Bromo-5-Chloro-2-Methoxyaniline
CAS No.	569688-63-7
Molecular Formula	C7H7BrClNO
Molecular Weight	236.49 g/mol
Synonyms	2-Methoxy-3-bromo-5-chloroaniline; 3-Bromo-5-chloro-o-anisidine; 5-Chloro-3-bromo-2-methoxyaniline; 2-Amino-6-bromo-4-chloroanisole; 1-Amino-3-bromo-5-chloro-2-methoxybenzene; Benzenamine, 3-bromo-5-chloro-2-methoxy-; 3-Bromo-5-chloro-2-methoxybenzenamine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-2-Methoxyaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and heat sources. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.