Description

3-Pyridazinecarboxylic Acid, Hexahydro-4-Hydroxy-, (3S,4R)- (9Ci) is a high-purity, stereochemically defined heterocyclic building block of significant synthetic interest. This compound matters as a versatile chiral synthon, enabling the construction of complex molecules with precise three-dimensional architecture for advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by academic and industrial chemists exploring new chemical space in medicinal chemistry and catalysis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Research: Used in the development of novel, stereoselective herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a scaffold for creating chiral ligands used in asymmetric synthesis and catalysis.
• Medicinal Chemistry Probe: Employed in structure-activity relationship (SAR) studies to explore the impact of the pyridazine core and hydroxyl group on biological activity.
• Chemical Biology Tool: Can be incorporated into molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Academic Research: A valuable compound for methodological studies in organic synthesis, particularly in stereoselective ring formation and functionalization.

Basic Information

Product Name	3-Pyridazinecarboxylic Acid, Hexahydro-4-Hydroxy-, (3S,4R)- (9Ci)
CAS No.	566917-34-8
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	(3S,4R)-Hexahydro-4-hydroxy-3-pyridazinecarboxylic acid; (3S,4R)-4-Hydroxyhexahydropyridazine-3-carboxylic acid; Hexahydro-4-hydroxy-3-pyridazinecarboxylic acid, (3S,4R)-; 4-Hydroxyhexahydropyridazine-3-carboxylic acid; (3S,4R)-4-Hydroxyperhydropyridazine-3-carboxylic acid; 3-Pyridazinecarboxylic acid, hexahydro-4-hydroxy-, (3S,4R)-; (3S,4R)-rel-4-Hydroxyhexahydro-3-pyridazinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Pyridazinecarboxylic Acid, Hexahydro-4-Hydroxy-, (3S,4R)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for demanding R&D applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.