Description

Potassium 3-Pyridyltrifluoroborate is an organoboron reagent belonging to the potassium trifluoroborate salt family, a highly valuable class of intermediates in modern synthetic chemistry. Its primary value lies in its enhanced stability and handling characteristics compared to boronic acids, making it a superior choice for robust cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for constructing complex pyridine-containing molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds, enabling the introduction of the 3-pyridyl moiety into complex molecular architectures.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs) and drug candidates containing pyridine rings, which are prevalent in many therapeutic agents.
• Agrochemical Development: Serves as a critical building block for creating novel herbicides, fungicides, and insecticides that incorporate pyridine-based structures for enhanced efficacy.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Facilitates the development of organic electronic materials, such as those used in OLEDs and conductive polymers, where pyridine units are integral.
• Chemical Biology & Probe Development: Useful for creating molecular probes and bioconjugates for studying biological systems and diagnostic applications.

Basic Information

Product Name	Potassium 3-Pyridyltrifluoroborate
CAS No.	561328-69-6
Molecular Formula	C5H4BF3KN
Molecular Weight	188.99 g/mol
Synonyms	Potassium (Pyridin-3-yl)trifluoroborate; 3-Pyridyltrifluoroborate Potassium Salt; Potassium (3-Pyridyl)trifluoroboronate; Potassium Pyridine-3-trifluoroborate; 3-Pyridyl-BF3K; 3-Pyridyl Potassium Trifluoroborate; Potassium 3-Pyridinyltrifluoroborate; 3-Pyridyl Trifluoroboronic Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 3-Pyridyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F), HPLC for purity assessment, and KF titration for moisture content, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. For long-term storage, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹¹B NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.