Description

2,8-Bis((tert-Butyldimethylsilyl)Oxy)Chromeno[4,3-C]Chromen-5(11H)-One is a high-purity, protected intermediate of significant interest in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex heterocyclic molecules and active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel chromene-based compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, particularly those with chromene or benzopyran scaffolds.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex molecular libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules in pilot plants and commercial manufacturing.
• Organic Synthesis Reagent: Acts as a protected dihydroxy compound, enabling selective reactions in complex synthetic sequences where sensitive functional groups are present.
• Academic Research: Utilized in universities and research institutes for studying novel organic reactions, heterocyclic chemistry, and the synthesis of natural product analogs.

Basic Information

Product Name	2,8-Bis((tert-Butyldimethylsilyl)Oxy)Chromeno[4,3-C]Chromen-5(11H)-One
CAS No.	554430-87-4
Molecular Formula	C29H40O5Si2
Molecular Weight	524.80 g/mol
Synonyms	2,8-Bis[(tert-butyldimethylsilyl)oxy]-5H-chromeno[4,3-c]chromen-5-one; 2,8-Bis-O-(tert-butyldimethylsilyl)-5H-chromeno[4,3-c]chromen-5-one; Chromeno[4,3-c]chromene-5(11H)-one, 2,8-bis[(1,1-dimethylethyl)dimethylsilyl]oxy]-; TBDMS-protected Chromenedione Intermediate; 2,8-Di-O-TBDMS Chromeno[4,3-c]chromen-5-one
EINECS	Contact for details

Quality Control

Our 2,8-Bis((tert-Butyldimethylsilyl)Oxy)Chromeno[4,3-C]Chromen-5(11H)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee consistency and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.