Description

n-(4-Bromo-2-Fluorophenyl)Methanesulfonamide CAS NO 549490-15-5 is a high-purity, specialized organic intermediate featuring a bromo-fluorophenyl core. This compound is critical for advanced chemical synthesis, offering a versatile building block for constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

This sulfonamide derivative serves as a key synthetic intermediate in several high-value industrial and research applications:

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure for bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialized polymers and advanced organic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the 4-bromo-2-fluorophenyl moiety into more complex molecules.
• Life Science Research: Utilized as a biochemical tool or probe in academic and industrial research laboratories for studying biological pathways.

Basic Information

Item	Details
Product Name	n-(4-Bromo-2-Fluorophenyl)Methanesulfonamide
CAS No.	549490-15-5
Molecular Formula	C7H7BrFNO2S
Molecular Weight	268.10 g/mol
Synonyms	4-Bromo-2-fluoro-N-(methylsulfonyl)aniline; N-(4-Bromo-2-fluorophenyl)methanesulfonamide; Methanesulfonamide, N-(4-bromo-2-fluorophenyl)-; 4-Bromo-2-fluoroaniline methanesulfonamide; 2-Fluoro-4-bromo-N-(methylsulfonyl)aniline; 549490-15-5; N-(4-Bromo-2-fluorophenyl)mesylamide
EINECS	Contact for details

Quality Control

Our production of n-(4-Bromo-2-Fluorophenyl)Methanesulfonamide adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.