Description

(R,R)-[2-(4'-I-Propyloxazolin-2'-Yl)Ferrocenyl]Diphenylphosphine, Min. 97% is a high-purity, chiral ferrocenyl phosphine-oxazoline ligand, a cornerstone in modern asymmetric catalysis. This compound matters for its exceptional ability to induce high enantioselectivity in a variety of transition-metal-catalyzed transformations, enabling the production of single-enantiomer intermediates critical for advanced materials and pharmaceuticals. Chemical manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical sectors require this ligand to develop efficient and sustainable synthetic routes for chiral molecules.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Asymmetric C-C Bond Formation: Employed in reactions such as allylic alkylation, hydroformylation, and conjugate addition to construct chiral carbon frameworks.
• Pharmaceutical Intermediate Synthesis: Critical for the production of enantiomerically pure active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators with specific biological activity.
• Fine Chemical and Fragrance Production: Facilitates the creation of high-value chiral flavor and fragrance compounds.
• Academic and Industrial R&D: A valuable tool for methodology development and exploring new catalytic asymmetric processes.
• Material Science: Potential use in the synthesis of chiral polymers and advanced functional materials.

Basic Information

Product Name	(R,R)-[2-(4'-I-Propyloxazolin-2'-Yl)Ferrocenyl]Diphenylphosphine, Min. 97%
CAS No.	541540-70-9
Molecular Formula	C32H32FeNOP
Molecular Weight	533.42 g/mol
Synonyms	(R,R)-Fe-IP; (R,R)-Ferrocenyl-IP; (R,R)-[2-(4'-Isopropyloxazolin-2'-yl)ferrocen-1-yl]diphenylphosphine; (R,R)-Josiphos-type ligand derivative; (R,R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyl-4-isopropyl-2-oxazoline; Chiral Ferrocenyl Phosphine-Oxazoline Ligand; (R,R)-Fc-IP; (R,R)-FcPHOX-iPr
EINECS	Contact for details

Quality Control

Our (R,R)-[2-(4'-I-Propyloxazolin-2'-Yl)Ferrocenyl]Diphenylphosphine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and chiral analysis, to confirm identity, chemical purity (≥97%), and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	Min. 97%
Enantiomeric Excess (Chiral HPLC)	Min. 99% ee
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.