Description

1,1Bis((2S,5S)-2,5-Di-I-Propylphospholano)Ferrocene, Min. 97% is a highly specialized chiral ferrocenyl phosphine ligand, a critical component in asymmetric catalysis. This compound matters because it enables the precise control of stereochemistry in chemical synthesis, leading to higher yields and purities of desired enantiomers. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and high-value intermediates.

Application

This chiral ligand is a cornerstone in advanced synthetic chemistry, enabling highly selective transformations.

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for producing single-enantiomer pharmaceutical building blocks.
• Pharmaceutical Intermediate Synthesis: Used in the development and scale-up of chiral active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and anti-infectives.
• Agrochemical Synthesis: Facilitates the production of enantiomerically pure herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Fine Chemical and Fragrance Manufacturing: Applied in the synthesis of complex, high-value chiral molecules for flavors, fragrances, and specialty materials.
• Academic and Industrial R&D: A vital tool for methodology development in asymmetric catalysis and exploring new reaction pathways in process chemistry.
• Catalyst Screening Libraries: Serves as a key component in high-throughput screening kits for identifying optimal catalytic conditions for challenging transformations.

Basic Information

Product Name	1,1Bis((2S,5S)-2,5-Di-I-Propylphospholano)Ferrocene, Min. 97%
CAS No.	540475-73-8
Molecular Formula	C26H44FeP2
Molecular Weight	474.42 g/mol
Synonyms	(S,S)-1,1'-Bis(2,5-diisopropylphospholano)ferrocene; Josiphos SL-J009-1; (S,S)-Josiphos; (S,S)-1,1'-Bis[(2,5-diisopropylphospholan-1-yl)]ferrocene; (S,S)-DiPPF; (2S,5S)-1,1'-Bis(2,5-diisopropylphospholano)ferrocene; (S,S)-1,1'-Bis(2,5-di-iso-propylphospholano)ferrocene; Ferrocenyl Josiphos ligand
EINECS	Contact for details

Quality Control

Every batch of our 1,1Bis((2S,5S)-2,5-Di-I-Propylphospholano)Ferrocene is manufactured and tested under strict quality management systems. We guarantee a minimum purity of 97%, with comprehensive analytical characterization to confirm identity, chiral purity, and impurity profiles. Certificates of Analysis (COA) detailing results from NMR, HPLC, and chiral analysis are provided to ensure traceability and batch-to-batch consistency for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen). Recommended storage temperature is 2-8°C for long-term stability. Handle and open containers in a controlled, moisture-free environment.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (NMR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Chiral Purity (Chiral HPLC)	Min. 99.0% ee
Solubility	Soluble in common organic solvents (THF, Toluene, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.