Description

2H-Pyran-3-Carbonitrile,Tetrahydro-2-Methyl-2-(1-Methylethyl)-,(2R,3R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its unique pyran ring structure and nitrile functionality, which serve as versatile building blocks for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide molecules where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Institutional Research: A valuable compound for methodological studies in organic synthesis and for teaching advanced concepts in stereochemistry.

Basic Information

Product Name	2H-Pyran-3-Carbonitrile,Tetrahydro-2-Methyl-2-(1-Methylethyl)-,(2R,3R)-Rel-(9Ci)
CAS No.	538368-49-9
Molecular Formula	C10H17NO
Molecular Weight	167.25 g/mol
Synonyms	(2R,3R)-rel-2-Isopropyl-2-methyltetrahydro-2H-pyran-3-carbonitrile; Tetrahydro-2-methyl-2-(1-methylethyl)-2H-pyran-3-carbonitrile, (2R,3R)-rel-; (rel-(2R,3R))-2-Isopropyl-2-methyltetrahydro-2H-pyran-3-carbonitrile; 2H-Pyran-3-carbonitrile, tetrahydro-2-methyl-2-(1-methylethyl)-, (2R,3R)-rel-; 538368-49-9; Chiral Dihydropyran Carbonitrile; Isopropylmethyltetrahydropyrancarbonitrile
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-3-Carbonitrile,Tetrahydro-2-Methyl-2-(1-Methylethyl)-,(2R,3R)-Rel-(9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as assay, enantiomeric excess, and impurity profile. We are committed to supplying material that meets the exacting requirements of process research and early-stage development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.