Description

4-Chloro-3-[[[[(4-Nitrophenoxy)Acetyl]Amino]Thioxomethyl]Amino]-Benzoic Acid is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture designed for targeted synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in research areas requiring specific thioxomethyl and nitrophenoxy functionalities. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and agrochemical industries for creating next-generation therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates, particularly in medicinal chemistry research.
• Agrochemical Research: Used in the development of new herbicides or pesticides, leveraging its specific chloro and nitro aromatic substructures.
• Chemical Biology Probe Synthesis: Employed to create specialized molecular probes for studying enzyme inhibition or receptor binding mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing bespoke compounds for client R&D projects.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in heterocyclic and amide bond chemistry.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized azo dyes or colorants due to its aromatic amine and nitro groups.

Basic Information

Product Name	4-Chloro-3-[[[[(4-Nitrophenoxy)Acetyl]Amino]Thioxomethyl]Amino]-Benzoic Acid
CAS No.	532432-50-1
Molecular Formula	C16H12ClN3O6S
Molecular Weight	409.80 g/mol
Synonyms	4-Chloro-3-({[(4-nitrophenoxy)acetyl]carbamothioyl}amino)benzoic acid; Benzoic acid, 4-chloro-3-[[[[(4-nitrophenoxy)acetyl]amino]thioxomethyl]amino]-; 3-[(Z)-{[(4-Nitrophenoxy)acetyl]carbamothioyl}amino]-4-chlorobenzoic acid; 4-Chloro-3-({[(4-nitrophenoxy)acetyl]carbamothioyl}amino)benzoic acid; 532432-50-1; 4-Chloro-3-({[(4-nitrophenoxy)acetyl]carbamothioyl}amino)benzoic acid (ACI); 4-Chloro-3-({[(4-nitrophenoxy)acetyl]carbamothioyl}amino)benzoic acid (IUPAC)
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-[[[[(4-Nitrophenoxy)Acetyl]Amino]Thioxomethyl]Amino]-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.