Description

Trifluoromethanesulfonic Acid 7-Methoxy-2,2-Dimethyl-4-Oxo-4H-1,3-Benzodioxin-5-Yl Ester is a specialized, high-purity chemical intermediate designed for advanced synthetic applications. This compound is valued for its role as a versatile trifluoromethanesulfonate (triflate) ester, enabling efficient functional group transformations under mild conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the 7-methoxy-2,2-dimethyl-4-oxo-4H-1,3-benzodioxin moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring this specific heterocyclic scaffold.
• Cross-Coupling Reactions: Serves as an excellent electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the superior leaving group ability of the triflate group.
• Material Science Research: Employed in the development of organic electronic materials and specialty polymers where its unique structure can impart specific electronic properties.
• Process Chemistry: Facilitates scalable, high-yield transformations in route scouting and optimization for commercial manufacturing processes.

Basic Information

Product Name	Trifluoromethanesulfonic Acid 7-Methoxy-2,2-Dimethyl-4-Oxo-4H-1,3-Benzodioxin-5-Yl Ester
CAS No.	532394-17-5
Molecular Formula	C13H11F3O7S
Molecular Weight	368.29 g/mol
Synonyms	5-(Trifluoromethanesulfonyloxy)-7-methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one; 7-Methoxy-2,2-dimethyl-4-oxo-4H-1,3-benzodioxin-5-yl trifluoromethanesulfonate; 5-Triflyloxy-7-methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one; Benzodioxin Triflate Ester; Triflate Ester of 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one
EINECS	Contact for details

Quality Control

Our Trifluoromethanesulfonic Acid 7-Methoxy-2,2-Dimethyl-4-Oxo-4H-1,3-Benzodioxin-5-Yl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation upon prolonged exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.