Description

3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-(2-Methylphenyl)-,(1S,4S,5R)-(9Ci) is a high-purity, stereochemically defined bicyclic lactone compound that serves as a critical chiral building block in advanced organic synthesis. Its unique fused ring structure and defined stereochemistry make it an invaluable intermediate for constructing complex molecular architectures with high precision. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific spatial orientation is crucial for biological activity.
• Asymmetric Catalysis Research: Serves as a sophisticated ligand precursor or substrate in the development of new catalytic systems for stereocontrolled reactions.
• Material Science: Potential monomer for synthesizing specialized polymers with unique thermal or mechanical properties derived from its rigid bicyclic framework.
• Academic & Process Chemistry: A valuable compound for methodological studies in organic synthesis, including ring-opening and functionalization reactions.

Basic Information

Item	Details
Product Name	3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-(2-Methylphenyl)-,(1S,4S,5R)-(9Ci)
CAS No.	528588-20-7
Molecular Formula	C14H16O2
Molecular Weight	216.28 g/mol
Synonyms	(1S,4S,5R)-4-Ethyl-1-(2-methylphenyl)-3-oxabicyclo[3.1.0]hexan-2-one; 4-Ethyl-1-o-tolyl-3-oxabicyclo[3.1.0]hexan-2-one; (1S,4S,5R)-rel-4-Ethyl-1-(2-methylphenyl)-3-oxabicyclo[3.1.0]hexan-2-one; Bicyclic Lactone Derivative; Chiral Bicyclic Lactone Intermediate; CAS 528588-20-7
EINECS	Contact for details

Quality Control

Every batch of 3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-(2-Methylphenyl)-,(1S,4S,5R)-(9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; consider storage under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.