Description

3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-(2-Fluorophenyl)-,(1S,4S,5R)-(9Ci) is a high-purity, stereochemically defined bicyclic lactone building block of significant interest in advanced organic synthesis. This compound is valued for its rigid, fused-ring scaffold and the presence of a fluorine atom, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, or insecticides, where the fluorine atom and bicyclic structure can enhance activity and environmental stability.
• Methodology Development: Employed in academic and industrial research to develop new asymmetric synthesis routes or catalytic transformations involving strained ring systems.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized chiral ligands or organocatalysts used in enantioselective reactions.
• Material Science Research: Investigated as a monomer or precursor for synthesizing specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	3-Oxabicyclo[3.1.0]Hexan-2-One,4-Ethyl-1-(2-Fluorophenyl)-,(1S,4S,5R)-(9Ci)
CAS No.	528588-17-2
Molecular Formula	C13H13FO2
Molecular Weight	220.24 g/mol
Synonyms	(1S,4S,5R)-4-Ethyl-1-(2-fluorophenyl)-3-oxabicyclo[3.1.0]hexan-2-one; (1S,4S,5R)-1-(2-Fluorophenyl)-4-ethyl-3-oxabicyclo[3.1.0]hexan-2-one; 4-Ethyl-1-(2-fluorophenyl)-3-oxabicyclo[3.1.0]hexan-2-one, (1S,4S,5R)-; Bicyclo[3.1.0]hexan-2-one, 3-oxa-4-ethyl-1-(2-fluorophenyl)-, (1S,4S,5R)-; Fluorophenyl Ethyl Oxabicyclohexanone; Chiral Fluorinated Lactone Building Block
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) that detail identity, purity, enantiomeric excess, and impurity profiles, ensuring traceability and compliance with research and cGMP standards for early-phase development. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.