Description

2H-Cyclopenta[B]Furan-2-One,Hexahydro-5-Hydroxy-4-(Hydroxymethyl)- is a high-purity, functionalized lactone derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily needed by research and development chemists in the pharmaceutical and fine chemical industries for applications such as the synthesis of active pharmaceutical ingredients (APIs) and novel specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for complex, stereochemically-defined targets.
• Fine Chemical Synthesis: Used as a versatile building block for constructing complex natural product analogs, flavors, and fragrances requiring specific lactone motifs.
• Asymmetric Catalysis Research: Acts as a valuable substrate or ligand precursor in the development and testing of new asymmetric catalytic methodologies.
• Polymer Chemistry: Potential monomer for the synthesis of specialized biodegradable or functional polymers due to its hydroxyl and lactone functionalities.
• Agrochemical Research: Investigated as an intermediate in the synthesis of advanced, biologically active compounds for crop protection.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	2H-Cyclopenta[B]Furan-2-One,Hexahydro-5-Hydroxy-4-(Hydroxymethyl)-
CAS No.	521323-11-5
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one; 4-(Hydroxymethyl)hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one; (3aR,4R,6R,6aR)-Tetrahydro-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2,6(3H)-diol; Functionalized Bicyclic Lactone; Chiral Lactone Diol; Advanced Pharmaceutical Intermediate
EINECS	Contact for details

Quality Control

Our 2H-Cyclopenta[B]Furan-2-One,Hexahydro-5-Hydroxy-4-(Hydroxymethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.