Description

Cyclohexanecarboxylic Acid, 4-[(2-Methylpropyl)Amino]-, cis- (9Ci) CAS NO 518336-29-3 is a specialized chiral amine derivative of cyclohexanecarboxylic acid, characterized by its cis-configuration and isobutylamino substituent. This compound is a high-value intermediate prized for its role in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry for efficacy.
• Ligand and Catalyst Precursor: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce stereoselectivity.
• Advanced Material Monomer: Employed in the research of specialty polymers and liquid crystals where the cyclohexane and amine functionality impart specific thermal and optical properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 4-[(2-Methylpropyl)Amino]-, cis- (9Ci)
CAS No.	518336-29-3
Molecular Formula	C11H21NO2
Molecular Weight	199.29 g/mol
Synonyms	cis-4-(Isobutylamino)cyclohexanecarboxylic acid; 4-(Isobutylamino)cyclohexanecarboxylic acid, cis-; cis-4-[(2-Methylpropyl)amino]cyclohexanecarboxylic acid; (1r,4r)-4-[(2-Methylpropyl)amino]cyclohexane-1-carboxylic acid; (1s,4s)-4-[(2-Methylpropyl)amino]cyclohexane-1-carboxylic acid; 4-(2-Methylpropylamino)cyclohexanecarboxylic acid (cis); cis-4-(Isobutylamino)-1-cyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 4-[(2-Methylpropyl)Amino]-, cis- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support cGMP and ISO compliant documentation for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric humidity. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% cis-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.