Description

4-Bromo-3,5-Difluorobenzenesulphonyl Chloride is a high-purity, multi-functional aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated and sulfonated structure, which enables precise chemical modifications for creating complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable and high-quality intermediate for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated aromatic core for enhanced bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, membranes, and advanced functional materials.
• Chemical Research: A versatile reagent for introducing the sulfonyl chloride functional group into complex molecules for further derivatization in medicinal chemistry and discovery labs.
• Dye and Pigment Industry: Intermediate for synthesizing specialized halogenated dyes and pigments with specific light-fastness and color properties.

Basic Information

Product Name	4-Bromo-3,5-Difluorobenzenesulphonyl Chloride
CAS No.	518057-63-1
Molecular Formula	C6H2BrClF2O2S
Molecular Weight	291.50 g/mol
Synonyms	4-Bromo-3,5-difluorobenzenesulfonyl chloride; 3,5-Difluoro-4-bromobenzenesulfonyl chloride; Benzenesulfonyl chloride, 4-bromo-3,5-difluoro-; 518057-63-1; 4-Br-3,5-F2-PhSO2Cl
EINECS	Contact for details

Quality Control

Our 4-Bromo-3,5-Difluorobenzenesulphonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.